A Brief Review on 3D Bioprinted Skin Substitutes

The global escalating cases of skin donor shortage for patients with severe wounds warn the vital need for alternatives to skin allografts. Over the last three decades, research in the skin regeneration area has addressed the unmet need for artificial skin substitutes. 3D bioprinting is a promising innovative technology to accurately fabricate skin constructs based on natural or synthetic bioinks, whether loaded or not loaded with native skin cells (i.e., keratinocytes and fibroblasts) or stem cells in the prescribed 3D hierarchal structure to create artificial multilayer and single cell-laden construct. In this paper, the recent developments in 3D bioprinting for skin regeneration are reviewed to discuss different aspects of skin bioprinted substitutes, including 3D printing technology, bioink composition, and cell-laden constructs. The impact of 3D printing parameters on functionality of the skin substitute and cell viability is reviewed to provide insight into controlled fabrication as the critical component of advanced wound healing. We highlight the recent and ongoing research in skin bioprinting to address the progress in the translation of advanced wound healing from lab to clinic

A Complete Model Characterization of Brushless DC Motors

The modeling problem associated with brushless DC motors (BLDCMs) with nonuniform air gaps which operate in a range where magnetic saturation may exist is addressed. The mathematical model, includes the effects of reluctance variations and magnetic saturation to guarantee proper modeling of the system. An experimental procedure is developed and implemented in a laboratory environment to identify the electromagnetic characteristics of a BLDCM in the presence of magnetic saturation. It is demonstrated that the modeling problem associated with this class of BLDCM can be formulated in terms of mathematically modeling a set of multidimensional surfaces corresponding to the electromagnetic torque function and the flux linkages associated with the motor phase windings. The accuracy of the mathematical model is checked against experimental measurement

Experimental Study for Improving the Productivity of Laser Foil Printing

This Study Aims to Improve the Productivity of Laser Foil Printing (LFP), Which is a Foil-Based Metal Additive Manufacturing (AM) Process. LFP Uses a Dual-Laser System to Fabricate a 3-Dimensional Part in a Layered Fashion by Performing Four Steps in Each Layer: Spot Welding, Pattern Welding, Contour Cutting, and Edge Polishing, All of Which Performed by Use of Lasers. We Experimentally Examined the Welding and Polishing Steps in This Study to Enhance LFP Productivity. the Jump Speed, Dwelling Duration, and Weld Path of Spot Welding and the Line Welding Speed and Wait Time between Weld Lines of Pattern Welding Are Determined to Minimize the LFP Processing Time, Resulting in an Eightfold Increase in Part Fabrication Productivity. Furthermore, We Introduce Laser Edge Polishing, vs. Mechanical Edge Polishing Done Previously, to Reduce the Edge Polishing Time and Further Increase the Productivity of the Automated LFP Process. for the Laser Polishing, We Study Laser Polishing Pattern (Line- or Spot-Type Polishing), Polishing Area, and overlapping Ratio

A Complete Model Characterization of Brushless DC Motors

The authors address the modeling problem associated with brushless DC motors (BLDCMs) with nonuniform air gaps that operate in a range where magnetic saturation may exist. The mathematical model includes the effects of reluctance variations as well as magnetic saturation to guarantee proper modeling of the system. An experimental procedure is developed and implemented in a laboratory environment to identify the electromagnetic characteristics of a BLDCM in the presence of magnetic saturation. It is demonstrated that the modeling problem associated with the class of BLDCMs can be formulated in terms of mathematically modeling a set of multidimensional surfaces corresponding to the electromagnetic torque function and the flux linkages associated with the motor phase windings. The accuracy of the mathematical model constructed by the developed method is checked against experimental measurement

Nonlinear Tracking Control of Brushless DC Motors for High-Performance Applications

The tracking control problem associated with brushless DC motors (BLDCMs) for high-performance applications is considered. To guarantee their high-dynamic-performance operation in motion control systems, the magnetic saturation and reluctance variation effects are accounted for in the BLDCM mathematical model. The trajectory tracking control problem is addressed in the context of the transformation theory of nonlinear systems. A nonlinear control law is implemented and shown to compensate for the nonlinearities of a BLDCM. A case study is presented in which a direct-drive inverted pendulum actuated by a BLDCM is used to investigate the effectiveness of the control law. The effectiveness of the proposed control in compensating for modeling errors, external disturbances, and measurement errors is demonstrate

Rapid Tooling by Integrating Electroforming and Solid Freeform Fabrication Techniques

This paper describes a rapid tooling process that integrates solid freeform fabrication (SFF) with electroforming to produce metal tools including molds, dies, and electrical discharge machining (EDM) electrodes. Based on experimental data analysis, the geometry and material of the SFF part, the properties of the electroformed metal, and the process parameters are significant factors that cause inaccuracy in the manufactured tools. Thermomechanical modeling and numerical simulation is used to determine the geometry of the SFF part and the electroform thickness for minimizing the manufacturing time and cost while satisfying the tooling accuracy requirement

The Effect of Cell Size and Surface Roughness on the Compressive Properties of ABS Lattice Structures Fabricated by Fused Deposition Modeling

Researchers looking to improve the surface roughness of acrylonitrile butadiene styrene (ABS) parts fabricated by fused deposition modeling (FDM) have determined that acetone smoothing not only achieves improved surface roughness but increases compressive strength as well. However, the sensitivity of ABS parts to acetone smoothing has not been explored. In this study we investigated FDM-fabricated ABS lattice structures of various cell sizes subjected to cold acetone vapor smoothing to determine the combined effect of cell size and acetone smoothing on the compressive properties of the lattice structures. The acetone-smoothed specimens performed better than the as-built specimens in both compression modulus and maximum load, and there was a decrease in those compressive properties with decreasing cell size. The difference between as-built and acetone-smoothed specimens was found to increase with decreasing cell size for the maximum load

Experimental Study of Polymer Electrolyte Membrane Fuel Cells using a Graphite Composite Bipolar Plate Fabricated by Selective Laser Sintering

Selective Laser Sintering (SLS) can be used to fabricate graphite composite bipolar plates with complex flow fields for Polymer Electrolyte Membrane (PEM) fuel cells. The additive manufacturing process can significantly reduce the time and cost associated with the research and development of bipolar plates as compared to other fabrication methods such as compression molding. In this study, bipolar plates with three different designs, i.e., parallel in series, interdigitated, and bio-inspired, were fabricated using the SLS process. The performance of these SLS-fabricated bipolar plates was studied experimentally within a fuel cell assembly under various operating conditions. The effect of temperature, relative humidity, and pressure on fuel cell performance was investigated. In the tests conducted for this study, the best fuel cell performance was achieved with a temperature of 75 ⁰C, relative humidity of 100%, and back pressure of 2 atm

Petri Net Modeling of a Flexible Assembly Station for Printed Circuit Boards

Petri net modeling approaches are presented for a flexible workstation for automatic assembly of printed circuit boards. In order to improve the productivity of such a system, the building of mathematical models is a crucial step. Concentrating on the operational aspects, the authors construct ordinary and temporal Petri net models for the AT&T FWS-200 physical flexible workstation. Three outcomes follow from such models. First, designers can have a better understanding of concurrency, synchronization, mutual exclusion, and sequential relations involved in the system control from the graphical representations of Petri nets. Second, the performance analysis of system operations under different settings can be conducted. Thus, the results can be used to help designers choose the best operational setting on a basis of the system parameters. Third, the models can be used as an aid for automatic generation of real-time control programs and construction of Petri-net-based simulation if needed. The approaches suggested can be generalized to many other applications of multirobot assembly systems

A Differential Equation Approach to Swept Volumes

An approach to the analysis of swept volumes is introduced. It is shown that every smooth Euclidean motion or sweep, can be identified with a first-order, linear, ordinary differential equation. This sweep differential equation provides useful insights into the topological and geometrical nature of the swept volume of an object. A certain class, autonomous sweeps, is identified by the form of the associated differential equation, and several properties of the swept volumes of the members of this class are analyzed. The results are applied to generate swept volumes for a number of objects. Implementation of the sweep differential equation approach with computer-based numerical and graphical methods is also discussed